Catalogue / Ipamorelin

Ipamorelin

A pentapeptide growth hormone secretagogue containing aminoisobutyric acid and two D-configured residues, none of which appear in a standard sequence table.

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Computed constants
Molecular formula C38H49N9O5
Average mass 711.85 Da
Monoisotopic mass 711.3857 Da
Written as Aib-His-D-2-Nal-D-Phe-Lys-NH2
ClassGrowth hormone secretagogues
DeterminationPeptide analysis, catalogue compound
Price 341 USD

Computed at build time from the composition shown on this page, not transcribed from a supplier datasheet.

Ipamorelin has an average molecular weight of 711.85 daltons and a monoisotopic mass of 711.3857 daltons. Identity is confirmed by matching the measured deconvoluted mass to that figure, and purity is reported separately by reversed-phase chromatography at 214 nm. The two numbers answer different questions and neither substitutes for the other.

01Composition
Written sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular formulaC38H49N9O5

This compound contains residues outside the standard twenty, so a theoretical mass cannot be derived from a one-letter sequence. The masses above are computed from the molecular formula instead.

This is not a technicality. A laboratory that computes an expected mass from a sequence lookup will get the wrong number for this compound, and will then either report a false mismatch or adjust the expectation to fit the measurement.

02 Expected electrospray ions
Positive mode, protonated
Charge m/z
[M+1H]+ 712.393
[M+2H]2+ 356.7

These are the ions an electrospray source is expected to produce for a neutral mass of 711.3857 daltons, computed from the monoisotopic mass and the proton mass. They are what a raw spectrum should show before deconvolution.

A report that gives only a deconvoluted mass without the charge states it was derived from cannot be checked. Deconvolution is a calculation, and a calculation whose inputs are not shown is an assertion.

03What goes wrong with this compound
Three of the five residues are non-proteinogenic. A laboratory that reasons from a one-letter sequence will compute the wrong theoretical mass, so the formula rather than the sequence is the reference.
The C-terminal amide is essential. A free acid synthesis is one dalton heavier and is a different compound with different activity.
D and L isomers at positions 3 and 4 are not separated by a conventional C18 column. A purity figure from an achiral method does not exclude the diastereomer, and the certificate should say so.

Every compound fails in its own way. A generic peptide method applied without regard to these specifics produces a number that looks like a result and is not one.

Short synthetic peptides, most carrying D-amino acids or unnatural residues that make them resistant to serum peptidases and invisible to sequence-only reasoning.

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04How it is determined

LC-MS identity against a certified reference standard, purity by RP-HPLC at 214 nm. D-isomers are not resolved by a conventional C18 column and are not claimed to be.

Where the delivered milligram figure matters rather than the percentage, net peptide content by combustion analysis and water by Karl Fischer are added, and the certificate carries a closed mass balance instead of a single purity number.

Determinations available
LC-MS identity Measured mass
RP-HPLC purity Area at 214 nm
Net peptide content Milligrams
Water content Karl Fischer
Counter-ion Ion chromatography
Bacterial endotoxins USP <85>
FAQIpamorelin

What is the molecular weight of Ipamorelin?

The average molecular weight is 711.85 daltons and the monoisotopic mass is 711.3857 daltons, computed from the molecular formula C38H49N9O5 shown on this page. Both figures are calculated rather than transcribed, so they can be checked against the stated composition.

How is Ipamorelin tested for purity and identity?

LC-MS identity against a certified reference standard, purity by RP-HPLC at 214 nm. D-isomers are not resolved by a conventional C18 column and are not claimed to be. Purity describes the chromatographable fraction only and is not the same quantity as the peptide mass delivered per vial.

What goes wrong when Ipamorelin is analysed?

Three of the five residues are non-proteinogenic. A laboratory that reasons from a one-letter sequence will compute the wrong theoretical mass, so the formula rather than the sequence is the reference.

What does Ipamorelin analysis cost at ANALYTON?

Peptide analysis, catalogue compound is priced at 341 US dollars, covering the determinations described on this page. Content, safety and elemental determinations are ordered alongside and are priced separately on the price list.

Updated 2026-09-01. Masses computed at build, not transcribed.