Catalogue / GHRP-2
GHRP-2
Also written as Pralmorelin.
A hexapeptide secretagogue with three D-residues and a naphthylalanine, C-terminally amidated.
| Molecular formula | C45H55N9O6 |
| Average mass | 817.97 Da |
| Monoisotopic mass | 817.4275 Da |
| Written as | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 |
| Class | Growth hormone secretagogues |
| Determination | Peptide analysis, catalogue compound |
| Price | 341 USD |
Computed at build time from the composition shown on this page, not transcribed from a supplier datasheet.
GHRP-2 has an average molecular weight of 817.97 daltons and a monoisotopic mass of 817.4275 daltons. Identity is confirmed by matching the measured deconvoluted mass to that figure, and purity is reported separately by reversed-phase chromatography at 214 nm. The two numbers answer different questions and neither substitutes for the other.
| Written sequence | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 |
| Molecular formula | C45H55N9O6 |
This compound contains residues outside the standard twenty, so a theoretical mass cannot be derived from a one-letter sequence. The masses above are computed from the molecular formula instead.
This is not a technicality. A laboratory that computes an expected mass from a sequence lookup will get the wrong number for this compound, and will then either report a false mismatch or adjust the expectation to fit the measurement.
| Charge | m/z |
|---|---|
| [M+1H]+ | 818.435 |
| [M+2H]2+ | 409.721 |
These are the ions an electrospray source is expected to produce for a neutral mass of 817.4275 daltons, computed from the monoisotopic mass and the proton mass. They are what a raw spectrum should show before deconvolution.
A report that gives only a deconvoluted mass without the charge states it was derived from cannot be checked. Deconvolution is a calculation, and a calculation whose inputs are not shown is an assertion.
| Tryptophan oxidises on storage and under light, adding 16 daltons. An oxidised batch shows a shoulder ahead of the main peak that is easy to integrate away. |
| The naphthylalanine residue absorbs strongly, which skews area-normalised purity if the calculation assumes uniform response. |
| Free acid rather than amide at the C-terminus is a routine synthesis failure and is one dalton heavier. |
Every compound fails in its own way. A generic peptide method applied without regard to these specifics produces a number that looks like a result and is not one.
Short synthetic peptides, most carrying D-amino acids or unnatural residues that make them resistant to serum peptidases and invisible to sequence-only reasoning.
LC-MS identity against a certified reference standard, purity by RP-HPLC at 214 nm. D-isomers are not resolved by a conventional C18 column and are not claimed to be.
Where the delivered milligram figure matters rather than the percentage, net peptide content by combustion analysis and water by Karl Fischer are added, and the certificate carries a closed mass balance instead of a single purity number.
| LC-MS identity | Measured mass |
| RP-HPLC purity | Area at 214 nm |
| Net peptide content | Milligrams |
| Water content | Karl Fischer |
| Counter-ion | Ion chromatography |
| Bacterial endotoxins | USP <85> |
What is the molecular weight of GHRP-2?
The average molecular weight is 817.97 daltons and the monoisotopic mass is 817.4275 daltons, computed from the molecular formula C45H55N9O6 shown on this page. Both figures are calculated rather than transcribed, so they can be checked against the stated composition.
How is GHRP-2 tested for purity and identity?
LC-MS identity against a certified reference standard, purity by RP-HPLC at 214 nm. D-isomers are not resolved by a conventional C18 column and are not claimed to be. Purity describes the chromatographable fraction only and is not the same quantity as the peptide mass delivered per vial.
What goes wrong when GHRP-2 is analysed?
Tryptophan oxidises on storage and under light, adding 16 daltons. An oxidised batch shows a shoulder ahead of the main peak that is easy to integrate away.
What does GHRP-2 analysis cost at ANALYTON?
Peptide analysis, catalogue compound is priced at 341 US dollars, covering the determinations described on this page. Content, safety and elemental determinations are ordered alongside and are priced separately on the price list.
Other compounds in this class
Updated 2026-09-01. Masses computed at build, not transcribed.